Prenatal Exposure to Bisphenol A Analogues on Male Reproductive Functions in Mice
نویسندگان
چکیده
منابع مشابه
Normal reproductive organ development in CF-1 mice following prenatal exposure to bisphenol A.
Bisphenol A (BPA) is a monomer used in the manufacture of a multitude of chemical products, including epoxy resins and polycarbonate. The objective of this study was to evaluate the effects of BPA on male sexual development. This study, performed in CF-1 mice, was limited to the measurement of sex-organ weights, daily sperm production (DSP), epididymal sperm count, and testis histopathology in ...
متن کاملHigh Prenatal Exposure to Bisphenol A Reduces Anogenital Distance in Healthy Male Newborns
OBJECTIVE To estimate the relationship between cord blood bisphenol A (BPA) levels and anogenital measurements in healthy newborns. METHODS Pregnancy and birth history, together with body mass and length data, anogenital measurements, penile measurements and cord blood samples were obtained from healthy newborns. Cord blood concentration of BPA was analyzed by sandwich enzyme-linked immunosor...
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Bisphenol A (BPA) is a chemical used in numerous consumer products that is able to interfere with the mammalian endocrine system. The aim of the present study was to investigate the effects of BPA on male mouse reproductive cells following prenatal to postnatal exposure. In addition, the influence of BPA was detected on the expression levels of β‑catenin and dickkopf WNT signaling pathway inhib...
متن کاملEffects of Pesticides on Male Reproductive Functions
Exposure to pesticides could be one of the contributing cause to the falling sperm counts and rising levels of male infertility. Adverse effects of pesticides in the environment first received widespread attention in the 1960s. However, only recently it has been postulated that long term, low exposure of these chemicals are increasingly linked to human health effects such as immuno-suppression,...
متن کاملAdverse effects of bisphenol A on male reproductive function.
BPA is a ubiquitous environmental contaminant, resulting mainly from manufacturing,use or disposal of plastics of which it is a component, and the degradation of industrial plastic-related wastes. Growing evidence from research on laboratory animals, wildlife, and humans supports the view that BPA produces an endocrine disrupting effect and adversely affects male reproductive function. To bette...
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ژورنال
عنوان ژورنال: Toxicological Sciences
سال: 2018
ISSN: 1096-6080,1096-0929
DOI: 10.1093/toxsci/kfy061